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Archive 2012 winter
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         1Çб⠠ /   2Çбâ

         Advanced Statistics and R Programming (2Çбâ)

         - °­ÀÇ ½Ã°£ : Åä¿äÀÏ ¿ÀÈÄ 1±³½Ã ¿ÀÈÄ 3:00 ~ 4:30
         - °­ÀÇ Àå¼Ò : ¼­¿ï´ëÇб³ ¿¬°ÇÄ·ÆÛ½º ÀÇ°ú´ëÇÐ

No ÀϽà °­ÀÇ ³»¿ë ´ã´ç°­»ç
1 2018³â 11¿ù 3ÀÏ Starting with R
- Introduction to R
- R installation, workspace, R package installation
- Basic R functions
2 11¿ù 10ÀÏ Data manipulation with R
- Data type
- Importing and exporting data
- Data management
- Missing values
3 11¿ù 17ÀÏ Review of Basic Statistics
- Probability distributions
- Summary statistics
- Hypothesis testing, confidence intervals, bootstrap
- Exploratory data analysis using R: basic graphics, correlation coefficients, contingency table
4 11¿ù 24ÀÏ [1¹Ú 2ÀÏ ÇÕ¼÷±³À°]
Statistical Analysis I: Analysis of means
- Distributions
- Parametric tests
- Non-Parametric tests
5 12¿ù 1ÀÏ Statistical Analysis II: Analysis of proportions and relations
- Correlation
- Regression
- ANOVA
6 12¿ù 8ÀÏ Survival Analysis
- Censoring, Survival data, Survival function
- Cox proportional-hazards regression
- Kaplan-Meier survival curve
- Statistical comparison of survival curves: log-rank, Wilcoxon test
7 12¿ù 15ÀÏ Machine learning algorithms for Biomedical Informatics
- Supervised analysis
- Unsupervised analysis
8 12¿ù 22ÀÏ Classification using R
- Feature selection - K-Nearest Neighbor
- Support Vector Machine
- Linear Discriminant Analysis
9 2019³â 1¿ù 5ÀÏ Evaluation and Validation
- Over-fitting
- Cross validation: train/validation/test set split
- Empirical p-value, permutation test - Multiple testing correction
10 1¿ù 12ÀÏ Advanced R graphics
- Line Plots, Bar charts, Histograms, Scatter plot
- Labels and legends
- Lattice package
11 1¿ù 19ÀÏ Microarray Data Analysis I
- Bioconductor packages
- Introduction to Microarray Data
- Normalization methods
12 1¿ù 26ÀÏ Microarray Data Analysis II
- Identifying DEG: t-test, SAM
- Volcano plot - FDR
- Probe annotation
13 2¿ù 16ÀÏ Gene ontology & Pathway analysis
- Gene clustering
- GO and Pathway enrichment analysis
- R packages for semantic similarity
14 2¿ù 23ÀÏ Case study: association of BRCA1 and BRCA2 mutations with survival in ovarian cancer (JAMA 2011) - DEG extraction from RNA-seq data - Clustering (K-means, hierarchical) - Correlation analysis between methylation and expression data - Survival analysis



         Á¤º¸ÀÇÇÐ °³·Ð II (2Çбâ)

         - °­ÀÇ ½Ã°£ : Åä¿äÀÏ 2±³½Ã ¿ÀÈÄ 4:50~6:20
         - °­ÀÇ Àå¼Ò : ¼­¿ï´ëÇб³ ¿¬°ÇÄ·ÆÛ½º ÀÇ°ú´ëÇÐ

No ÀϽà °­ÀÇ ³»¿ë ´ã´ç°­»ç
1 2018³â 11¿ù 3ÀÏ °Ç°­Á¤º¸½Ã½ºÅÛ EMR/EHR/PHR
2 11¿ù 10ÀÏ ¸í»ç ÃÊû Ư°­ - Network Biology À̱⿵
3 11¿ù 17ÀÏ µ¥ÀÌÅÍ¿þ¾îÇϿ콺 ±¸Ãà°ú µ¥ÀÌÅ͸¶ÀÌ´× ¹Ú·¡¿õ
4 11¿ù 24ÀÏ [1¹Ú 2ÀÏ ÇÕ¼÷±³À°]
4 12¿ù 1ÀÏ ¸í»ç ÃÊû Ư°­ - Datamining and its application in Biomedical Informatics ½ÅÇöÁ¤
5 12¿ù 8ÀÏ ÀÇ·áÁ¤º¸¿Í ȯÀÚÁÖµµÇü °Ç°­ ½Ã½ºÅÛ
6 12¿ù 15ÀÏ ¸í»ç ÃÊû Ư°­ - Lessons from 1000 Genome Project
7 12¿ù 22ÀÏ ÀÇ·áÁ¤º¸¿Í °³ÀÎÁ¤º¸º¸È£
8 2019³â 1¿ù 5ÀÏ ¸í»ç ÃÊû Ư°­ - Markov Chain and Hidden Markov Model ¼Õ°æ¾Æ
9 1¿ù 12ÀÏ ¸í»ç ÃÊû Ư°­ - SNOMED CT ¹ÚÇö¾Ö
10 1¿ù 19ÀÏ ¸í»ç ÃÊû Ư°­ - Gamification and mHealth ±èÁ¤Àº
12 1¿ù 26ÀÏ ¸í»ç ÃÊû Ư°­ - Àӻ󿬱¸/ÀÓ»ó½ÃÇèÁ¤º¸½Ã½ºÅÛ ÃÖÀοµ
13 2¿ù 16ÀÏ ¸í»ç ÃÊû Ư°­ - Drug Repositioning ÀοëÈ£
14 2¿ù 23ÀÏ ¸í»ç ÃÊû Ư°­ - Semantic Web ¼Õ¿µ¼ö



         Bioinformatics : Genomic Medicine (2Çбâ)

         - °­ÀÇ ½Ã°£ : Åä¿äÀÏ 3±³½Ã Àú³á 7:30 ~ 9:00
         - °­ÀÇ Àå¼Ò : ¼­¿ï´ëÇб³ ¿¬°ÇÄ·ÆÛ½º ÀÇ°ú´ëÇÐ

No ÀϽà °­ÀÇ ³»¿ë ´ã´ç°­»ç
1 2018³â 11¿ù 3ÀÏ TCGA data introduction
2 11¿ù 10ÀÏ Advanced Microarray Data Analysis
3 11¿ù 17ÀÏ Next Generation Sequencing & Personal Genome Data Analysis
4 11¿ù 24ÀÏ [1¹Ú 2ÀÏ ÇÕ¼÷±³À°]NGS Platforms and Application
5 12¿ù 1ÀÏ Personal Genome Interpretation
6 12¿ù 8ÀÏ RNA-Seq Expression Profile Analysis
7 12¿ù 15ÀÏ Sequence-level Transcriptome Analysis
8 12¿ù 22ÀÏ Non-Coding RNAs in RNA-Seq Data
9 2019³â 1¿ù 5ÀÏ Identifing Genomic rearrangement, Gene fusion analysis from RNA sequence
10 1¿ù 12ÀÏ Exome Sequencing and Cancer Genome Bioinformatics
11 1¿ù 19ÀÏ Copy Number and Genomic Rearrangement
12 1¿ù 26ÀÏ GWAS and Post-GWAS, eQTL data Analysis
13 2¿ù 16ÀÏ PheWAS, EWAS and Electronic Medical Records Data Analysis
14 2¿ù 23ÀÏ ±â¸»°í»ç